[Martian]

In all-other-factors-being-equal theory, 2.5” drives (like this Little Big Disk) should be more rugged and vibration resistant than 3.5” drives for the same reason an ant can lift 10 times its own weight and a toy truck can fall out of a second story window without damage.
Also, 2.5” drive mechanisms arguably are (or should be) designed for the mechanical shock and thermal shock mobile environment — laptops and mobile enclosures.
Just thinking outside the box — anyone care to comment?

[macmanmk]

LaCie drives are absolute garbage. We had 7 of 12 die from standard desktop use. If you read a few of the other comments here, maybe we needed to throw the whole lot in a backpack and trek all over Canada. Maybe that would have extended the life of these unreliable pieces of trash.

[DHart]

I recently opened up some LaCie drives that were bought from about two years ago up to a couple of months ago and found Maxtor and Samsung drives inside. From what I've read, Maxtor drives aren't so great. Overall I've had excellent luck with the LaCies I've bought over the last twelve years or so, but these days I only buy OWC external cases and separate hard drive mechanisms which I install myself so I know what's what and can shuffle drives around as I see fit without voiding any warranties when I open the cases. My current choices are OWC Mercury cases with Seagate Barracuda and Hitachi Deskstar 3.5" drives inside. In the 2.5" drive market, Hitachi is my choice and is leading the market segment.
I've bought a few RAID 0 dual drives from LaCie which have functioned fine, but I didn't know I was buying RAID 0. Now, I'll never buy a RAID 0 set-up as the risk of failure and data loss is much greater than with two single drives (read TimeMachine!) or a RAID 1 set-up.
A PASS on this little LaCie.

[DHart]

TO add: my fave set-up is the OWC Mercury ELite enclosure that houses two 3.5" drives... I use the drives independently. One of them is a 750 GB Hitachi Deskstar that serves as my primary and the other is a 1 TB Seagate Barracuda set up as a TimeMachine drive to cover my bases every hour on the hour. Sweet! Frys.com frequently offers the 1 TB Seagate for $189 on weekly special!!!